科學研究：

研究方向：

從事天然藥物合成生物學研究。

承擔科研項目情況：

1.非糧油能源植物的含油量與脂肪酸組成等指標的分析”，國家基礎性重大項目之子課題。

2.植物三萜類物質生物合成相關基因的挖掘，中國科學院“百人計劃”，2010-2012。

3.白黎蘆醇的生物合成，Supported by the National Science Foundation of the United States，No.MCB0519634, 2005-2006，主要參加。

4.青蒿素生物合成相關基因的克隆與功能鑒定，Supported by the National Research Council of Canada’s Crop for Enhanced Human Health Program, 2006-2008，主要參加。

科研成果：

資料更新中……

論文專著：

目前已在Journal of The American Chemical Society、Journal of Biological Chemistry、New Phytologist、Plant Physiology、Plant Biotechnology Journal、Phytochemistry、 Planta Medica等著名期刊上發(fā)表研究論文10多篇。

發(fā)表英文論文：

1.Jian-chun Qin,Lin Zhu,Ming-jun Gao, Xian Wu, Hong-yu Pan, Yansheng Zhang*, Xiang Li*,Cloning and functional characterization of a chalcone isomerase from Trigonella foenum-graecum L. Planta Medica, 2010,in press (*corresponding author).

2.Changchun Ruan, Zhi Liu, Xiang Li, Xia Liu, Lijuan Wang, Yinan Zhen, Guangzhi Sun, Yansheng Zhang, and Lianxue Zhang, Isolation and charaterization of a new ginsenoside from the fresh root of Panax ginseng. Molecules, 2010, 15:2319-2325.

3.Hao Zhang, Guangzhi Sun, Xiang Li, Hongyu Pan*, and Yansheng Zhang*, A new geldanamycin analogue from Streptomyces hygroscopicus. Molecules, 2010, 15: 1161-1167 (* corresponding author).

4.Yansheng Zhang, Goska Nowak, Darwin W. Reed, Patrick S. Covello, The engineering of artemisinin precursor production in tobacco. Plant Biotechnology Journal,2010, in press.

5.Lies Maes*, Filip Nieuwerburgh*, Yansheng Zhang*, Darwin W. Reed, Jacob Pollier, Sofie R.F. Vande Casteele, Dirk Inze, Patrick S. Covello, Dieter L.D. Deforce and Alain Goossens, Dissection of the response of Artemisia annua plants to phytohormones identifies genes involved in terpene biosynthesis and the development of glandular trichomes. New Phytologist, 2010, in press (* co- first author).

6.Devin R. Polichuk*, Yansheng Zhang*, Darwin W. Reed, Janice F. Schmidt, Patrick S. Covello, A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua. Phytochemistry, 2010, 71: 1264-1269(* co-first author).

7.Yansheng Zhang, Keat H. Teoh, Darwin W. Reed, Patrick S. Covello, Molecular cloning and characterization of Dbr1, a 2-alkenal reductase from Artemisia annua. Botany, 2009, 87: 643- 649.

8.Yansheng Zhang, Keat H. Teoh, Darwin W. Reed, Lies Maes, Alain Goossens, Douglas J.F. Olson, Andrew R.S. Ross, and Patrick S. Covello, The molecular cloning of artemisinic aldehyde Δ 11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua. J. Biol. Chem., 2008, 283 (31): 21501-21508.

9.Yansheng Zhang, Teoh, Keat, Reed, Darwin W., Olson, Douglas J.H., Andrew, Ross R.S., Covello, Patrick S. Nuceotide sequence encoding sesquiterpene double bond reductase. US Patent No 11977-98 (filed on Dec. 11/2008).

10.Zhang J, Subramanian S, Zhang Y, Yu O, Flavone synthases from Medicago truncatula are flavanone-2-hydroxylases and are important for nodulation. Plant Physiology, 2007, 144: 741-751.

11.Zhang Y, Liu ZH, Jia L, Peng ZL, Jaworski J, Wang XM, Jez J., Chen F, Yu O , Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and mammalian cells. Journal of The American Chemical Society.2006,128: 13030-13031. Featured in Chemical and Engineering News, 84 (Oct. 2, 2006): page 43.

12.Jun-Li Han, Hong Wang, He-Chun Ye, Yan Liu, Yan-sheng Zhang, Fang Yan, Guofeng Li, High efficiency of genetic transformation and regeneration of Artemisia annua. via Agrobacterium tumefaciens-mediated procedure , Plant Science, 2005, 168( 1): 73-80.

13.Yansheng Zhang, Hechun Ye, Guofeng Li, Molecular Cloning a classical plant peroxidase from A. annua and its effect on the biosynthesis of artemisinin in vitro, Acta Botanica Sinica, 2004, 46(11): 1338-1346.

14.Yansheng Zhang, Hechun Ye, Guofeng Li, Effect of a horseradish peroxidase on the biosynthesis of artemisinin in Artemisia annua in vitro, Chinese Journal of Applied and Environmental Biology,2003, 9 (6) 616- 618.

15.Yansheng Zhang, Rimao Hua,Yongde Yue, Feng Tang, Studies on antifeedant activity of cnidium Monnieri against the larvae of Pieris rapae L, Journal of AnHui Agricultural University, 2002, 29 (4): 333-335 (in Chinese).

發(fā)表中文論文：

1 PCR-RAPD分子生物學技術及其在植物抗病性研究中的應用 李淼; 檀根甲; 趙彥; 周冬生; 章焰生; 江佳富; 吳新安; 承河元 安徽農業(yè)大學植保系; 中國科學院科學時報社; 軍事醫(yī)學科學院微生物流行病研究所; 中國科學院植物研究所; 軍事醫(yī)學科學院毒物藥物研究所; 安徽農業(yè)大學植保系 合肥 【期刊】生物技術通訊 2003-04-30

2 辣根過氧化物酶在體外條件下對青蒿素生物合成的影響(英文) 章焰生; 葉和春; 李國鳳 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室; 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室; 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室 北京 【期刊】應用與環(huán)境生物學報 2003-12-28

3 辣根過氧化物酶在體外條件下對青蒿素生物合成的影響 章焰生; 葉和春; 李國鳳 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室; 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室 【會議】中國植物學會七十周年年會論文摘要匯編（1933—2003） 2003-06-30

4 青蒿不同生長期青蒿素、青蒿酸含量的消長變化以及受赤霉酸調控的研究 章焰生; 葉和春; 李國鳳 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室; 中國科學院植物研究所光合作用與環(huán)境分子生理學重點實驗室 【會議】中國植物學會七十周年年會論文摘要匯編（1933—2003） 2003-06-30

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榮譽獎勵：

1.2009年底入選中國科學院“百人計劃”。

資料更新中……